Phytanoyl-CoA dioxygenase Sequence and Evolution: Difference between revisions
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== Phylogenetic Trees == | == Phylogenetic Trees == | ||
*Both trees show animals and fungi most highly | *Both trees show animals and fungi most highly conserved and plants least conserved | ||
*PhyD required for the breakdown of fatty acids in the diet of animals and fungi | |||
*Original tree similar to consensus tree except for two protozoans | *Original tree similar to consensus tree except for two protozoans | ||
*Monosiga brevicollis and tetrahymena thermophila both have low bootstrap values but some possibility of lateral gene transfer in the case of tetrahymena | *Monosiga brevicollis and tetrahymena thermophila both have low bootstrap values but some possibility of lateral gene transfer in the case of tetrahymena |
Revision as of 01:10, 10 June 2008
Fasta Sequence
>gi|134105315|pdb|2OPW|A Chain A, Crystal Structure Of Human Phytanoyl-Coa Dioxygenase Phyhd1 (Apo) MACLSPSQLQKFQQDGFLVLEGFLSAEECVAMQQRIGEIVAEMDVPLHCRTEFSTQEEEQLRAQGSTDYF LSSGDKIRFFFEKGVFDEKGNFLVPPEKSINKIGHALHAHDPVFKSITHSFKVQTLARSLGLQMPVVVQS MYIFKQPHFGGEVSPHQDASFLYTEPLGRVLGVWIAVEDATLENGCLWFIPGSHTSGVSRRMVRAPVGSA PGTSFLGSEPARDNSLFVPTPVQRGALVLIHGEVVHKSKQNLSDRSRQAYTFHLMEASGTTWSPENWLQP TAELPFPQLYT
Multiple Sequence Alignment
- 46 analogous sequence compared using ClustalX
- Multiple Sequence Alignment is of high quality and conservation
- Fe2+ and 2-Oxogylterate binding sites shown
Phylogenetic Trees
- Both trees show animals and fungi most highly conserved and plants least conserved
- PhyD required for the breakdown of fatty acids in the diet of animals and fungi
- Original tree similar to consensus tree except for two protozoans
- Monosiga brevicollis and tetrahymena thermophila both have low bootstrap values but some possibility of lateral gene transfer in the case of tetrahymena