Strings 2008 1 1: Difference between revisions
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== 1 Background: Biological sequences == | == 1 Background: Biological sequences == | ||
* DNA, RNA, protein | |||
** universal molecules of life (from tiny micro-organisms to large mammals) | |||
** state the chemical structure of DNA, RNA and protein | |||
*** [http://en.wikipedia.org/wiki/DNA DNA]: 4 nucleotides, double helix, base pairing | |||
*** [http://en.wikipedia.org/wiki/RNA RNA]: 4 nucleotides, single stranded | |||
*** [http://en.wikipedia.org/wiki/Protein protein]: 20 amino acids, complex 3D structure | |||
* [http://en.wikipedia.org/wiki/Central_dogma central dogma of molecular biology] | |||
** = transfer of sequence information from DNA (mastercopy) to RNA (blueprint) to protein (construct) | |||
** introduce terminology: transcription and translation | |||
** universal code of life (from tiny micro-organisms to large mammals) | |||
** introduce the concepts of reading frames and reverse compliment | |||
* [http://en.wikipedia.org/wiki/Evolution evolution] and [http://en.wikipedia.org/wiki/Tree_of_life_%28science%29 tree of life] | |||
** discuss how organisms are related (evolution) and how this relations can be represented (tree of life) | |||
Reading material: | |||
[[Media:chapter1_introduction.pdf | Chapter 1 from Zvelebil and Baum's Understanding bioinformatics]]<br> | [[Media:chapter1_introduction.pdf | Chapter 1 from Zvelebil and Baum's Understanding bioinformatics]]<br> | ||
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[[strings_2008_2_1| goto Comparing sequences]] | [[strings_2008_2_1| goto Comparing sequences]] | ||
--[[User:ThomasHuber|ThomasHuber]] 15:26, 17 January 2008 (EST) | |||
Latest revision as of 04:26, 17 January 2008
1 Background: Biological sequences
- DNA, RNA, protein
- central dogma of molecular biology
- = transfer of sequence information from DNA (mastercopy) to RNA (blueprint) to protein (construct)
- introduce terminology: transcription and translation
- universal code of life (from tiny micro-organisms to large mammals)
- introduce the concepts of reading frames and reverse compliment
- evolution and tree of life
- discuss how organisms are related (evolution) and how this relations can be represented (tree of life)
Reading material:
Chapter 1 from Zvelebil and Baum's Understanding bioinformatics
--ThomasHuber 15:26, 17 January 2008 (EST)
