2gnx Results: Difference between revisions
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A Dali analysis (Table 1) of our protein was highly inconclusive and there were no significant structural matches to our hypothetical protein. | A Dali analysis (Table 1) of our protein was highly inconclusive and there were no significant structural matches to our hypothetical protein. | ||
Table 1: A Dali analysis of the 2GNX protein | |||
NR. STRID1 STRID2 Z RMSD LALI LSEQ2 %IDE REVERS PERMUT NFRAG TOPO PROTEIN | NR. STRID1 STRID2 Z RMSD LALI LSEQ2 %IDE REVERS PERMUT NFRAG TOPO PROTEIN | ||
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98: 3023-A 2e9x-A 2.6 1.3 53 144 6 0 0 2 S REPLICATION DNA replication complex gins protein psf1 | 98: 3023-A 2e9x-A 2.6 1.3 53 144 6 0 0 2 S REPLICATION DNA replication complex gins protein psf1 | ||
99: 3023-A 2d4x-A 2.6 4.3 94 214 12 0 0 10 S STRUCTURAL PROTEIN flagellar hook-associated protein 3 | 99: 3023-A 2d4x-A 2.6 4.3 94 214 12 0 0 10 S STRUCTURAL PROTEIN flagellar hook-associated protein 3 | ||
A Dali analysis carried out separately with the N-terminus and the C-terminus of the protein showed us that |
Revision as of 05:37, 11 June 2007
Structural analysis
A Dali analysis (Table 1) of our protein was highly inconclusive and there were no significant structural matches to our hypothetical protein.
Table 1: A Dali analysis of the 2GNX protein
NR. STRID1 STRID2 Z RMSD LALI LSEQ2 %IDE REVERS PERMUT NFRAG TOPO PROTEIN 1: 3023-A 2gnx-A 42.9 0.0 280 280 100 0 0 1 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION hypothetical pro 2: 3023-A 2cmr-A 5.7 3.5 114 192 11 0 0 11 S IMMUNOGLOBULIN COMPLEX d5 (fab heavy chain) d5 (fab li 3: 3023-A 1j3w-A 5.7 3.2 99 134 12 0 0 9 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION giding protein-m 4: 3023-A 1jmr-A 5.5 3.0 94 246 9 0 0 12 S 5: 3023-A 1f5m-B 5.5 5.0 107 177 9 0 0 13 S SIGNALING PROTEIN gaf (saccharomyces cerevisiae) yeas 6: 3023-A 1vcs-A 5.0 4.7 82 102 9 0 0 8 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION vesicle transpor 7: 3023-A 1kt0-A 4.9 2.8 81 357 6 0 0 7 S ISOMERASE 51 kda fk506-binding protein (fkbp51) Mutant 8: 3023-A 1e2a-A 4.9 4.5 80 102 9 0 0 6 S TRANSFERASE enzyme iia (enzyme iii, lactose-specific i 9: 3023-A 2d2s-A 4.8 3.1 75 217 11 0 0 5 S ENDOCYTOSIS/EXOCYTOSIS exocyst complex component exo84 10: 3023-A 2oew-A 4.7 2.8 119 358 8 0 0 12 S PROTEIN TRANSPORT programmed cell death 6-interacting 11: 3023-A 1h3q-A 4.7 4.2 92 140 4 0 0 11 S TRANSPORT sedlin (sedl) (mus musculus) mouse S.B.Jan 12: 3023-A 2oev-A 4.5 36.5 151 697 7 0 0 14 S PROTEIN TRANSPORT programmed cell death 6-interacting 13: 3023-A 2cwy-A 4.5 2.4 82 92 20 0 0 7 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION hypothetical pro 14: 3023-A 2c5i-T 4.5 2.8 75 93 11 0 0 5 S PROTEIN TRANSPORT/COMPLEX t-snare affecting a late gol 15: 3023-A 3nul 4.4 3.4 93 130 5 0 0 11 S ACTIN-BINDING PROTEIN profilin i (arabidopsis thalian 16: 3023-A 2h7o-A 4.4 3.0 81 270 5 0 0 7 S SIGNALING PROTEIN protein kinase ypka fragment (protei 17: 3023-A 1mc0-A 4.4 13.3 144 341 9 0 0 17 S HYDROLASE 3',5'-cyclic nucleotide phosphodiesterase 2a 18: 3023-A 2ijp-A 4.3 4.2 117 217 13 0 0 12 S SIGNALING PROTEIN 14-3-3 protein (cryptosporidium par 19: 3023-A 2h7v-C 4.3 4.2 76 269 13 0 0 5 S SIGNALING PROTEIN migration-inducing protein 5 (ras-re 20: 3023-A 2cbi-A 4.3 4.3 123 584 7 0 0 13 S HYDROLASE hyaluronidase fragment expression_system_ve 21: 3023-A 1hg5-A 4.3 3.2 85 263 9 0 0 6 S ENDOCYTOSIS clathrin assembly protein short form frag 22: 3023-A 2dnx-A 4.2 4.9 80 130 6 0 0 6 S TRANSPORT PROTEIN syntaxin-12 fragment (homo sapiens) 23: 3023-A 1a17 4.2 5.0 85 159 4 0 0 8 S HYDROLASE serineTHREONINE PROTEIN PHOSPHATASE 5 fragme 24: 3023-A 2if4-A 4.1 2.5 82 258 7 0 0 7 S SIGNALING PROTEIN atfkbp42 fragment (twd1 (twisted dwa 25: 3023-A 1owa-A 4.0 3.3 76 156 12 0 0 6 S CYTOKINE spectrin alpha chain, erythrocyte fragment (e 26: 3023-A 1br0-A 4.0 3.5 79 120 13 0 0 6 S MEMBRANE PROTEIN syntaxin 1-a fragment Mutant (rattus 27: 3023-A 1xdo-A 3.9 3.5 83 686 10 0 0 8 S TRANSFERASE polyphosphate kinase (ppk, polyphosphoric 28: 3023-A 1vls 3.9 3.6 77 146 10 0 0 7 S CHEMOTAXIS aspartate receptor (tar) biological_unit ( 29: 3023-A 1sjj-A 3.9 7.9 114 863 4 0 0 14 S CONTRACTILE PROTEIN actinin (gallus gallus) chicken 30: 3023-A 2iak-A 3.8 2.4 68 197 6 0 0 5 S CELL ADHESION bullous pemphigoid antigen 1, isoform 5 31: 3023-A 2dl1-A 3.8 4.1 86 116 3 0 0 7 S PROTEIN TRANSPORT spartin fragment (trans-activated by 32: 3023-A 2h28-A 3.7 2.8 75 106 8 0 0 10 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION hypothetical pro 33: 3023-A 2cwo-A 3.7 3.3 83 165 5 0 0 10 S RNA BINDING PROTEIN RNA silencing suppressor (p21) (b 34: 3023-A 2hj9-C 3.6 3.4 80 210 5 0 0 10 S SIGNALING PROTEIN autoinducer 2-binding periplasmic pr 35: 3023-A 2gsc-A 3.6 3.7 74 113 12 0 0 5 S UNKNOWN FUNCTION conserved hypothetical protein (conse 36: 3023-A 2cpt-A 3.6 4.0 78 117 12 0 0 5 S PROTEIN TRANSPORT vacuolar sorting protein 4b fragment 37: 3023-A 1v9d-A 3.6 4.4 83 308 5 0 0 6 S PROTEIN BINDING diaphanous protein homolog 1 fragment 38: 3023-A 2i0m-A 3.5 4.5 113 207 10 0 0 13 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION phosphate transp 39: 3023-A 2hje-A 3.5 3.2 84 210 7 0 0 11 S SIGNALING PROTEIN autoinducer 2 sensor kinasePHOSPHATA 40: 3023-A 2dmw-A 3.5 3.3 85 131 7 0 0 11 S MEMBRANE PROTEIN synaptobrevin-like 1 variant fragment 41: 3023-A 2bkp-A 3.5 3.3 84 193 7 0 0 8 S HYPOTHETICAL PROTEIN hypothetical protein ph0236 (pyr 42: 3023-A 1zu2-A 3.5 5.2 73 158 5 0 0 6 S TRANSPORT PROTEIN mitochondrial import receptor subuni 43: 3023-A 1y79-1 3.5 3.1 93 680 4 0 0 10 S HYDROLASE peptidyl-dipeptidase dcp (dipeptidyl carboxy 44: 3023-A 2fup-A 3.4 2.9 80 126 9 0 0 7 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION hypothetical pro 45: 3023-A 2iub-A 3.3 4.7 79 331 11 0 0 5 S MEMBRANE PROTEIN divalent cation transport-related pro 46: 3023-A 2e9x-D 3.3 2.5 66 197 3 0 0 6 S REPLICATION DNA replication complex gins protein psf1 47: 3023-A 2bkn-A 3.3 3.3 80 190 6 0 0 5 S MEMBRANE PROTEIN hypothetical protein ph0236 (pyrococ 48: 3023-A 2avx-A 3.3 3.7 94 171 5 0 0 10 S TRANSCRIPTION regulatory protein sdia Mutant (escheri 49: 3023-A 1u89-A 3.3 3.1 77 139 4 0 0 6 S STRUCTURAL PROTEIN talin 1 fragment (talin) (mus musc 50: 3023-A 1qqt-A 3.3 3.4 84 546 7 0 0 6 S LIGASE methionyl-trna synthetase fragment (escherichi 51: 3023-A 1qqe-A 3.3 7.4 94 281 6 0 0 10 S PROTEIN TRANSPORT vesicular transport protein sec17 Mu 52: 3023-A 2j3t-C 3.2 5.2 83 141 7 0 0 8 S PROTEIN TRANSPORT trafficking protein particle complex 53: 3023-A 1uur-A 3.2 3.2 84 460 7 0 0 7 S SIGNAL TRANSDUCTION stat protein fragment (dictyostel 54: 3023-A 1tkn-A 3.2 3.8 75 110 13 0 0 5 S MEMBRANE PROTEIN amyloid beta a4 protein (homo sapien 55: 3023-A 1qja-A 3.2 3.0 75 217 5 0 0 8 S COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 14-3-3 protein z 56: 3023-A 1ek8-A 3.2 5.6 78 185 9 0 0 5 S TRANSLATION ribosome recycling factor (ribosome relea 57: 3023-A 2uv0-E 3.1 3.6 94 159 9 0 0 12 S TRANSCRIPTION transcriptional activator protein lasr ( 58: 3023-A 2nty-A 3.1 2.6 93 332 4 0 0 9 S SIGNALING PROTEIN emb|cab41934.1 fragment (prone8) rac 59: 3023-A 2hi7-B 3.1 2.6 77 134 5 0 0 8 S OXIDOREDUCTASE thiol:disulfide interchange protein dsb 60: 3023-A 2fez-A 3.1 3.6 104 373 10 0 0 12 S TRANSCRIPTION probable regulatory protein embr (mycob 61: 3023-A 2a73-B 3.1 3.2 91 976 11 0 0 13 S IMMUNE SYSTEM complement c3 fragment complement c3 fra 62: 3023-A 1uw4-B 3.1 3.3 86 247 12 0 0 12 S NONSENSE MEDIATED MRNA DECAY PROTEIN regulator of nons 63: 3023-A 1hx1-B 3.1 3.2 76 112 13 0 0 6 S CHAPERONE/CHAPERONE INHIBITOR heat shock cognate 71 k 64: 3023-A 1fpo-A 3.1 3.4 72 171 8 0 0 4 S CHAPERONE chaperone protein hscb (hsc20) Mutant (esc 65: 3023-A 2o8p-A 3.0 5.0 104 215 13 0 0 11 S SIGNALING PROTEIN 14-3-3 domain containing protein (c 66: 3023-A 2d9d-A 3.0 3.8 80 89 13 0 0 8 S CHAPERONE bag family molecular chaperone regulator 5 f 67: 3023-A 2ak6-A 3.0 5.7 93 153 8 0 0 11 S 68: 3023-A 1ya0-A 3.0 4.3 81 458 6 0 0 8 S SIGNALING PROTEIN smg-7 transcript variant 2 fragment 69: 3023-A 1x8z-A 3.0 3.2 75 151 9 0 0 3 S PROTEIN BINDING invertasePECTIN METHYLESTERASE INHIBIT 70: 3023-A 1qoy-A 3.0 7.5 121 303 14 0 0 9 S TOXIN hemolysin e (cytolysin a, silent hemolysin a, hl 71: 3023-A 1qgr-A 3.0 2.7 79 871 5 0 0 7 S TRANSPORT RECEPTOR importin beta subunit (karyopherin 72: 3023-A 1ocr-C 3.0 3.8 94 261 7 0 0 9 S OXIDOREDUCTASE cytochrome c oxidase (ferrocytochrome c 73: 3023-A 1fce 3.0 2.5 60 629 10 0 0 5 S CELLULASE DEGRADATION cellulase celf fragment (clostr 74: 3023-A 2nwb-A 2.9 3.8 88 379 6 0 0 10 S OXIDOREDUCTASE conserved domain protein (putative 2,3- 75: 3023-A 2i6h-A 2.9 3.8 92 176 10 0 0 12 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION hypothetical pro 76: 3023-A 1w5d-A 2.9 3.7 91 458 7 0 0 10 S HYDROLASE penicillin-binding protein (bacillus subtil 77: 3023-A 1sj7-A 2.9 5.5 77 167 10 0 0 5 S STRUCTURAL PROTEIN talin 1 fragment (mus musculus) mo 78: 3023-A 1ojg-A 2.9 3.5 83 135 8 0 0 8 S TRANSFERASE sensor protein dcus (dcus) fragment (esch 79: 3023-A 1i1i-P 2.9 3.6 100 665 7 0 0 10 S HYDROLASE neurolysin (rattus norvegicus) rat express 80: 3023-A 1dov-A 2.9 4.9 76 181 9 0 0 6 S CELL ADHESION alpha-catenin fragment (mus musculus) m 81: 3023-A 2grg-A 2.8 3.2 68 98 10 0 0 8 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION hypothetical pro 82: 3023-A 2bvl-A 2.8 3.6 90 543 14 0 0 9 S TOXIN toxin b fragment Mutant (clostridium difficile) 83: 3023-A 1z0p-A 2.8 1.6 51 73 4 0 0 2 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION hypothetical pro 84: 3023-A 1u6g-C 2.8 5.3 79 1146 6 0 0 9 S LIGASE cullin homolog 1 (cul-1) ring-box protein 1 (rb 85: 3023-A 1oj5-A 2.8 2.8 68 105 3 0 0 7 S TRANSCRIPTIONAL COACTIVATOR steroid receptor coactivat 86: 3023-A 1ecr-A 2.8 2.8 65 305 6 0 0 7 S COMPLEX (DNA-BINDING PROTEIN/DNA) replication terminat 87: 3023-A 1e25-A 2.8 4.6 92 278 7 0 0 9 S HYDROLASE extended-spectrum beta-lactamase per-1 Muta 88: 3023-A 1di1-A 2.8 4.4 72 290 4 0 0 5 S LYASE aristolochene synthase (sesquiterpene cyclase, 89: 3023-A 2p0n-A 2.7 3.1 80 157 10 0 0 7 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION hypothetical pro 90: 3023-A 2iiu-A 2.7 3.8 77 203 8 0 0 7 S STRUCTURAL GENOMICS/UNKNOWN FUNCTION hypothetical prot 91: 3023-A 2gom-A 2.7 2.4 54 61 6 0 0 5 S CELL ADHESION/TOXIN fibrinogen-binding protein fragmen 92: 3023-A 1z1w-A 2.7 4.3 98 780 5 0 0 12 S HYDROLASE tricorn protease interacting factor f3 (the 93: 3023-A 1h3n-A 2.7 3.6 76 813 14 0 0 6 S AMINOACYL-TRNA SYNTHETASE leucyl-trna synthetase (the 94: 3023-A 1bk5-A 2.7 3.0 71 422 7 0 0 8 S PROTEIN TRANSPORT karyopherin alpha fragment (importin 95: 3023-A 1aqt 2.7 1.7 47 135 0 0 0 2 S HYDROLASE atp synthase fragment Mutant (escherichia c 96: 3023-A 2nw9-A 2.6 6.4 102 265 9 0 0 11 S OXIDOREDUCTASE tryptophan 2,3-dioxygenase (xanthomona 97: 3023-A 2iml-A 2.6 2.5 59 188 8 0 0 4 S FLAVOPROTEIN hypothetical protein (archaeoglobus fulg 98: 3023-A 2e9x-A 2.6 1.3 53 144 6 0 0 2 S REPLICATION DNA replication complex gins protein psf1 99: 3023-A 2d4x-A 2.6 4.3 94 214 12 0 0 10 S STRUCTURAL PROTEIN flagellar hook-associated protein 3
A Dali analysis carried out separately with the N-terminus and the C-terminus of the protein showed us that