Protein Structure: Difference between revisions
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5: 3028-A 2db0-A 8.1 3.3 148 239 14 0 0 13 S PROTEIN BINDING 253aa long hypothetical protein (hypot | 5: 3028-A 2db0-A 8.1 3.3 148 239 14 0 0 13 S PROTEIN BINDING 253aa long hypothetical protein (hypot | ||
6: 3028-A 1b3u-A 8.0 27.7 150 588 13 0 0 13 S SCAFFOLD PROTEIN protein phosphatase pp2a fragment | 6: 3028-A 1b3u-A 8.0 27.7 150 588 13 0 0 13 S SCAFFOLD PROTEIN protein phosphatase pp2a fragment | ||
'''ClustalW Results''' | '''ClustalW Results''' | ||
Using the scores and results from DALI, a multiple sequence alignment was created with ClustalW. The sequences used were: | Using the scores and results from DALI, a multiple sequence alignment was created with ClustalW. The sequences used were: | ||
*2i2o Structural Genomics, unknown function | |||
*1hu3 Translation eif4gii fragment | |||
*1uw4 nonsense mediated mRNA decay protein | |||
*1h6k Nuclear Protein | |||
(refer to DALI table if unsure) | (refer to DALI table if unsure) | ||
Generally, the alignment shows | Generally, the alignment shows PATHETIC HOMOLOGY between these 4 sequences, which were already the best sequences that DALI could give. To view results, click here | ||
[http://www.ebi.ac.uk/cgi-bin/clustalw/result?tool=clustalw&jobid=clustalw-20070513-02332481&treendisp=hide&treetype=new&sortby=seqno&color=yes] | |||
'''Articles''' | '''Articles''' |
Revision as of 01:52, 13 May 2007
The so-called MIF4G domain found in several other proteins involved in RNA metabolism. (Mazza et al.)(PDB no: 1H6K)
- Coordinates assembly of translational machinery
DALI results
- SUMMARY: PDB/chain identifiers and structural alignment statistics
NR. STRID1 STRID2 Z RMSD LALI LSEQ2 %IDE REVERS PERMUT NFRAG TOPO PROTEIN 1: 3028-A 2i2o-A 37.1 0.0 206 206 100 0 0 1 S STRUCTURAL GENOMICS, UNKNOWN FUNCTION eif4g-like prote 2: 3028-A 1hu3-A 15.2 2.7 164 204 23 0 0 12 S TRANSLATION eif4gii fragment (eukaryotic initiation f 3: 3028-A 1uw4-B 10.9 3.6 164 247 9 0 0 12 S NONSENSE MEDIATED MRNA DECAY PROTEIN regulator of nons 4: 3028-A 1h6k-A 10.6 3.9 175 728 11 0 0 11 S NUCLEAR PROTEIN cbp80 fragment (ncbp 80 kda subunit, 5: 3028-A 2db0-A 8.1 3.3 148 239 14 0 0 13 S PROTEIN BINDING 253aa long hypothetical protein (hypot 6: 3028-A 1b3u-A 8.0 27.7 150 588 13 0 0 13 S SCAFFOLD PROTEIN protein phosphatase pp2a fragment
ClustalW Results
Using the scores and results from DALI, a multiple sequence alignment was created with ClustalW. The sequences used were:
- 2i2o Structural Genomics, unknown function
- 1hu3 Translation eif4gii fragment
- 1uw4 nonsense mediated mRNA decay protein
- 1h6k Nuclear Protein
(refer to DALI table if unsure)
Generally, the alignment shows PATHETIC HOMOLOGY between these 4 sequences, which were already the best sequences that DALI could give. To view results, click here [1]
Articles
A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery. (PDB no:1HU3) [2]
Crystal structure of the human nuclear cap binding complex. (PDB no: 1H6K) [3]
Novel eIF4G domain homologues linking mRNA translation with nonsensemediated mRNA decay [4]
- This article is quite relevant to protein function