ATP binding domain 4
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Investigation of The Functional, Structural and Evolutionary Components of ATP Binding Domain 4
Dali-Arginosuccinate synthase- pp-loop- function- catalyse hydrolysis of AB bond of ATP. RXN same wt atp pyrophosphatase
ATP binding domain 4 probably binds ATP –conserved motif SGGKD at the N terminus
Argininosuccinate synthetase works by:
L-citrullin + L-Asp + ATP = AMP + PP +
Substrate might be involved in tRNA replication Function can be inferred based on structures of the proteins-compare structures from available structures. Based on the comparison – found PP-loop- local structural motifs which are conserved across all species
ATP binding domain 4 Functions