Role in Human
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Role in Human
- OMIM
- Haloacid dehalogenase-like hydrolase domain
- Gene map locus 20p11
Dephosphorylation of Neu5Ac-9-P is a reversible reaction with an end product of Neu5Ac (sialic acid) and a free phosphate.
- Main form of sialic acid in vertebrates
- Important roles in protein-protein and cell-cell recognition
- Dependent on the presence of Mg2+
- Inhibited by vanadate and Ca2+