Arylformamidase Structure
1. Structure of Arylformamidase
Arylformamidase
The image above shows the chains A (upper right), B (upper left), C (lower right) & D (lower left) interacting. The molecules in the middle of chains A & B and chains C & D is phosphate ion (PO4). The green molecule between chain B & D is a magnesium ion (Mg).
Chain A of arylformamidase
The red molecule in the middle is an unknown ligand containing a ring composed of 9 oxygen molecules. The green sphere is a chloride ion.
2. Putative Thioesterase
Thioesterases split ester groups into acid and alcohol in the presence of water, specifically at a thiol group.
Thioesterases or thiolester hydrolases are members of E.C.3.1.2.
Our structure resembles carboxylesterases (hydrolases) hence it is predicted that it has similar cellular activity.
3. Interaction of human arylformamidase (AFMID) with other proteins
This image was generated from "STRING" database.
4. DALI OUTPUT
Metagenomic Archea Carboxylesterase A chain
PDB link title
Archaeoglobus fulgidus Carboxylesterase (Chains A B C D)
File:Carboxylesterase (archaeon).txt
PDB link title
5. Secondary structure analysis
PDBSum output for arylformamidase
PDBSUM [1]
Archeon Carboxylesterase secondary structure