Phytanoyl-CoA dioxygenase Structure
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Originally, the structure of our protein was experimentally defined (by Zhang, Z., Butler, D., McDonough, M.A et.al.) via X-ray diffraction.
Name - Phytanoyl-CoA dioxygenase (PHYHD1)
Resolution (Amstrongs) - 1.90
R-Value - 0.221 (obs, relatively low)
Space Group - P 3.1 2 1
Unit Cell Paramters (Amstrongs) - a = 91.97, b = 91.97, c = 81.61
Unit Cell Angles - alpha = 90.00, beta = 90.00, gamma = 120.00
Figure 1
Using Pymol the protein was visualized. This image was taken from behind the pocket of the molecule, it can be seen there is huge steric hinderance and no way for the ligand to enter.
Using Pymol the protein was visualized. This image was taken from behind the pocket of the molecule, it can be seen there is huge steric hinderance and no way for the ligand to enter.
Figure 1
Using Pymol the protein was visualized. Structurally, the pocket can be seen in this picture, this is the area in which the ligand enters and binds.
Using Pymol the protein was visualized. Structurally, the pocket can be seen in this picture, this is the area in which the ligand enters and binds.
Figure 1
Showing the topology of the protein. Reproduced from the European Bioinformatics Institute,
http://www.ebi.ac.uk/thornton-srv/databases/pdbsum/2opw/domA01.gif
Showing the topology of the protein. Reproduced from the European Bioinformatics Institute,
http://www.ebi.ac.uk/thornton-srv/databases/pdbsum/2opw/domA01.gif
Figure 2
Showing another topology of the protein. Reproduced from the European Bioinformatics Institute,
http://www.ebi.ac.uk/
Showing another topology of the protein. Reproduced from the European Bioinformatics Institute,
http://www.ebi.ac.uk/
