Function: Siowwei

Results on Function Analysis

2.1 Protein-interaction annotation: Table 2.1 Complete annotation of NUBP2 retrieved from UnitProtKB/Swiss-Prot

Names and origin

Protein names	Nucleotide-binding protein 2 Also known as:     NBP 2
Gene names	Name:  NUBP2
Organism	Homo sapiens (Human)

General annotation (Comments)

Function	May contribute to formation of bipolar spindles (By similarity).
Subunit structure	Binds NUBP1 and KIFC1 (By similarity).
Subcellular location	Nucleus (By similarity). Note=Associated with nucleus during interphase and nucleocytoplasm surrounding mitotic spindles during early mitosis. Enriched around centrosomes during late mitosis (By similarity).
Tissue specificity	Widely expressed with highest expression in skeletal muscle.
Developmental stage	Expressed in fetal brain, lung, liver and kidney.
Sequence similarities	Belongs to the Mrp/NBP35 ATP-binding proteins family.

Ontologies

Keywords
Cellular component	Nucleus
Ligand	ATP-bindingNucleotide-binding
Gene Ontology (GO)
Molecular function	Nucleotide binding Traceable author statement. Source: ProtInc

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view
Molecule processing
	Chain	1 – 271	271	Nucleotide-binding protein 2
Regions
	Nucleotide binding	22 – 29	8	ATP Potential	2.2 Sequence analysis

Table 2.2 Aligned sequence of 2ph1 protein

Table 2.3 The diagram and table below show the 3 sequence motifs found in the sequence

Table 2.4 The diagram and table below show the 1 sequence of superfamily found in the sequence

Figure 1. Protein-protein interactions search using 2ph1 sequence

Figure 2. Protein-protein interactions search using NUBP2 sequence

Figure 3. NUBP2 expressions in human and mouse tissues