2i2O Abstract

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Translation is important in expressing different genes in every cell of every organism. The evolution of eukaryotic organisms meant the need for a more complicated translation structure. An important part of initiating translation in eukaryotes is the eIF4G protein domain. The exact function of this domain and the proteins it encodes for is still not fully understood. This domain contains three identified smaller domains that all encode proteins that have specific functions in intiating translation and binding mRNA. The midddle domain was first isolated from the zebrafish Danio rerio. I

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