2i2O Conclusion: Difference between revisions
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Thus based on the information gathered that the function of MIF4G Domain Containing Protein is to bind RNA in such a way that allows the initiation of translation. It is possible that this mechanism is what facillitates binding of eIF4G to eIF4A. Functional sites have been identified at residues ''x y and z'' that further justify this conclusion. All information gathered was based on the assumption that the MIF4G-like protein from Danio Renio is significantly similar both structurally and functionally to MIF4G such that inferrences can be made in relation to one from the other. This is justified by extensive database analysis showing significant sequence identity and high structural similarity as well as identical protein locations and properties. | Thus based on the information gathered that the function of MIF4G Domain Containing Protein is to bind RNA in such a way that allows the initiation of translation. It is possible that this mechanism is what facillitates binding of eIF4G to eIF4A. Functional sites have been identified at residues ''x y and z'' that further justify this conclusion. All information gathered was based on the assumption that the MIF4G-like protein from Danio Renio is significantly similar both structurally and functionally to MIF4G such that inferrences can be made in relation to one from the other. This is justified by extensive database analysis showing significant sequence identity and high structural similarity as well as identical protein locations and properties. | ||
It should be mentioned that all of the above information is based on database searching and that further information is required for more specific predictions as to the function and structure of the protein. Future studies may wish to undertake experimental analysis that will help to isolate and identify key residues, binding sites | It should be mentioned that all of the above information is based on database searching and that further information is required for more specific predictions as to the function and structure of the protein. Future studies may wish to undertake experimental analysis that will help to isolate and identify key residues, binding sites and subsequent function. | ||
Revision as of 01:23, 12 June 2007
The next step in this process is to take the predictions made about the MIF4G domain containing protein and undertake experiments on the protein. This would confirm the usefulness of constructing a particular protein by using computational methods.
Thus based on the information gathered that the function of MIF4G Domain Containing Protein is to bind RNA in such a way that allows the initiation of translation. It is possible that this mechanism is what facillitates binding of eIF4G to eIF4A. Functional sites have been identified at residues x y and z that further justify this conclusion. All information gathered was based on the assumption that the MIF4G-like protein from Danio Renio is significantly similar both structurally and functionally to MIF4G such that inferrences can be made in relation to one from the other. This is justified by extensive database analysis showing significant sequence identity and high structural similarity as well as identical protein locations and properties.
It should be mentioned that all of the above information is based on database searching and that further information is required for more specific predictions as to the function and structure of the protein. Future studies may wish to undertake experimental analysis that will help to isolate and identify key residues, binding sites and subsequent function.
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