3b5q Function: Difference between revisions

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'''Predicted Functional Partners'''    
'''Predicted Functional Partners'''    
BT3796 Putative secreted sulfatase ydeN (518 aa)    
BT3796: Putative secreted sulfatase ydeN (518 aa).    
BT1595 Transcription termination factor rho (722 aa)    
BT1595 Transcription termination factor rho (722 aa).    
BT1597 Two-component system sensor histidine kinase (539 aa)    
BT1597 Two-component system sensor histidine kinase (539 aa).    
BT3057 N-acetylgalactosamine-6-sulfatase (508 aa)    
BT3057 N-acetylgalactosamine-6-sulfatase (508 aa).    
BT1598 Putative two-component system sensor histidine (655 aa)    
BT1598 Putative two-component system sensor histidine (655 aa).    
BT3101 N-sulphoglucosamine sulphohydrolase (455 aa)    
BT3101 N-sulphoglucosamine sulphohydrolase (455 aa).    
BT3489 Arylsulfatase B {UniProtKB/TrEMBL-Q8A219} (458 aa)  
BT3489 Arylsulfatase B {UniProtKB/TrEMBL-Q8A219} (458 aa).  





Revision as of 02:42, 21 May 2008

1. Function of sulfatases

Sulfatases are enzymes,which hydrolyse sulfate ester bonds of substrates. Most of the family members has shown to contain a highly conserved cystine residue and a bivalent metal binding site.


2. Functional site

MSA data revealed some conserved residues on the sequence. They were mapped on the three dimantional structure.

Zn Cl surface.png
























3. Arylsulfatase K (BT1596) Interactions with other proteins

Net.png


Input Protein BT1596 Putative sulfatase yidJ (481 aa) (Bacteroides thetaiotaomicron)

Predicted Functional Partners BT3796: Putative secreted sulfatase ydeN (518 aa). BT1595 Transcription termination factor rho (722 aa). BT1597 Two-component system sensor histidine kinase (539 aa). BT3057 N-acetylgalactosamine-6-sulfatase (508 aa). BT1598 Putative two-component system sensor histidine (655 aa). BT3101 N-sulphoglucosamine sulphohydrolase (455 aa). BT3489 Arylsulfatase B {UniProtKB/TrEMBL-Q8A219} (458 aa).





























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