3b5q Function: Difference between revisions

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'''Input Protein'''    
'''Input Protein'''    
BT1596 Putative sulfatase yidJ (481 aa)    
*BT1596 Putative sulfatase yidJ (481 aa)    
(Bacteroides thetaiotaomicron)    
(Bacteroides thetaiotaomicron)    


'''Predicted Functional Partners'''    
'''Predicted Functional Partners'''    
BT3796: Putative secreted sulfatase ydeN (518 aa).    
*BT3796: Putative secreted sulfatase ydeN (518 aa).    
BT1595 Transcription termination factor rho (722 aa).    
*BT1595 Transcription termination factor rho (722 aa).    
BT1597 Two-component system sensor histidine kinase (539 aa).    
*BT1597 Two-component system sensor histidine kinase (539 aa).    
BT3057 N-acetylgalactosamine-6-sulfatase (508 aa).    
*BT3057 N-acetylgalactosamine-6-sulfatase (508 aa).    
BT1598 Putative two-component system sensor histidine (655 aa).    
*BT1598 Putative two-component system sensor histidine (655 aa).    
BT3101 N-sulphoglucosamine sulphohydrolase (455 aa).    
*BT3101 N-sulphoglucosamine sulphohydrolase (455 aa).    
BT3489 Arylsulfatase B {UniProtKB/TrEMBL-Q8A219} (458 aa).  
*BT3489 Arylsulfatase B {UniProtKB/TrEMBL-Q8A219} (458 aa).  





Revision as of 02:45, 21 May 2008

1. Function of sulfatases

Sulfatases are enzymes,which hydrolyse sulfate ester bonds of substrates. Most of the family members has shown to contain a highly conserved cystine residue and a bivalent metal binding site.


2. Functional site

MSA data revealed some conserved residues on the sequence. They were mapped on the three dimantional structure.

Zn Cl surface.png
























3. Arylsulfatase K (BT1596) Interactions with other proteins

Net.png


Input Protein

  • BT1596 Putative sulfatase yidJ (481 aa)

(Bacteroides thetaiotaomicron)

Predicted Functional Partners

  • BT3796: Putative secreted sulfatase ydeN (518 aa).
  • BT1595 Transcription termination factor rho (722 aa).
  • BT1597 Two-component system sensor histidine kinase (539 aa).
  • BT3057 N-acetylgalactosamine-6-sulfatase (508 aa).
  • BT1598 Putative two-component system sensor histidine (655 aa).
  • BT3101 N-sulphoglucosamine sulphohydrolase (455 aa).
  • BT3489 Arylsulfatase B {UniProtKB/TrEMBL-Q8A219} (458 aa).





























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