3b5q Function

1. Function of sulfatases

Sulfatases are enzymes,which hydrolyse sulfate ester bonds of substrates. Most of the family members has shown to contain a highly conserved cystine residue and a bivalent metal binding site.

2. Functional site

MSA data revealed some conserved residues on the sequence. They were mapped on the three dimantional structure.

3. Arylsulfatase K (BT1596) Interactions with other proteins

Input Protein

• BT1596 Putative sulfatase yidJ (481 aa)(Bacteroides thetaiotaomicron)

Predicted Functional Partners

• BT3796: Putative secreted sulfatase ydeN (518 aa).
• BT1595 Transcription termination factor rho (722 aa).
• BT1597 Two-component system sensor histidine kinase (539 aa).
• BT3057 N-acetylgalactosamine-6-sulfatase (508 aa).
• BT1598 Putative two-component system sensor histidine (655 aa).
• BT3101 N-sulphoglucosamine sulphohydrolase (455 aa).
• BT3489 Arylsulfatase B {UniProtKB/TrEMBL-Q8A219} (458 aa).

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