ATP binding domain 4

Investigation of The Functional, Structural and Evolutionary Components of ATP Binding Domain 4

Introductions

Methods

Discussions

Dali-Arginosuccinate synthase- pp-loop- function- catalyse hydrolysis of AB bond of ATP. RXN same wt atp pyrophosphatase ATP binding domain 4 probably binds ATP –conserved motif SGGKD at the N terminus Argininosuccinate synthetase works by: L-citrullin + L-Asp + ATP = AMP + PP +

Substrate might be involved in tRNA replication Function can be inferred based on structures of the proteins-compare structures from available structures. Based on the comparison – found PP-loop- local structural motifs which are conserved across all species

ATP binding domain 4 Functions

ATP binding domain 4 Structures

ATP binding domain 4 Evolution

http://string.embl.de/ Type 'ATP n-type pyrophosphatase' Click PF1758