Abstract 2ece

Selenium binding protein is apart of the SBP56 superfamily of 56kDa selenium binding proteins. It consists of 8% helices (7 in total) and 40% beta sheets (36 in total). The protein can be found in a wide variety of organisms with evidence to support lateral gene transfer. It is predicted to be involved in the metabolism of toxic levels of selenium and tranportation in and around the golgi apparatus. It could also be invovled in the immune systems defenses against cancer.

The project was completed with a number of tools for each aspect. Bioinformatic databases such as pubmed, genbank, uniprot and pdb were utilised to gather litrature information, programs including psiblast, clustulx, protdist, neighbor, treeview and consense were used to analyse the gene homology, while Dali and PDBsum were used to anylise the structure. The functions were determined using literature and programs such as profunc and string. These tools were essential in creating this report and obtaining the conclusions drawn from it.

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