Arylformamidase Function Slide 2

Evidence from Similar Sequences

- Screening of BLAST result (see Sebastien) for functional information.

Selected results of the BLAST search as performed by Basma.

- Plethora of putative assignments.

- First paper with functional information (associated literature) - Pabarcus 2006.

- Catalytic triad identified in paper - Ser162, Asp247, and His279.

- To assess functional similarity, conservation of the catalytic triad was analysed.

Conservation of the catalytic triad between Arylformamidase and 2pbl.

- Aspartic acid --> Glutamic acid - Semi-conservative: both polar, acidic.

...Previous slide | Return to the main page | Next slide...