Arylformamidase Function Slide 5: Difference between revisions

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- To assess functional similarity, conservation of the catalytic triad was analysed.  
- To assess functional similarity, conservation of the catalytic triad was analysed.  


[[Image:2c7b_alignment2.png|centre|framed|'''Conservation of the catalytic triad between 2cb7 and 2pbl.''']]
[[Image:Catalytic triad conversation.PNG|centre|framed|'''DALI alignment showing conservation of the catalytic triad between 2C7B and 2PBL.''']]


- Catalytic triad conserved.
- Similar level of conservation as noted between 2PBL and arylformamidase.
 
- Note: difference in clustalW alignment from DALI sequence alignment. Unstable region of alignment?


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Latest revision as of 23:33, 9 June 2008

Evidence from Similar Structures

- Catalytic triad identified in paper - Ser154, Asp251, and His281.

- To assess functional similarity, conservation of the catalytic triad was analysed.

DALI alignment showing conservation of the catalytic triad between 2C7B and 2PBL.

- Similar level of conservation as noted between 2PBL and arylformamidase.

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