Arylformamidase Function Slide 7: Difference between revisions

From MDWiki
Jump to navigationJump to search
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:HSL_alignment.png|centre|framed|'''Sequence similarity in regions characteristic to the HSL family of lipases as identified by Arpigny and Jaeger (1999).''']]
== Identification of family. ==


== Thermostable? ==
- Byun, et al. (2007) alluded to the HSL family of lipases.


- Byun, et al. (2007) identified a number of HSL family members with thermostable properties.
- All known structures of the HSL family of esterases (Byun, et al. 2007) are present in the DALI search.


[[Image:DALI2pbl.png|centre|framed|'''Thermophillic HSL family members as identified by Byun, et al. 2007 found in the DALI search performed by Basma.''']]
[[Image:DAL_HSLs.png|centre|framed|'''Structures of the HSL family of esterases as identified by Byun, et al. (2007) present in the DALI results.''']]


[[Image:HSL_thermophillic_alignment.png|centre|framed|'''ClustalW alignment of 2pbl with thermophillic HSL family members as identified by Byun 2007.''']]
- 2pbl shares sequence similarity in regions characteric to the HSL family of esterases (Arpigny and Jaeger 1999).


- Similar sequence in regions characteristic to this family of proteins (Arpigny and Jaeger 1999).
[[Image:HSL_alignment.png|centre|framed|'''Sequence similarity in regions characteristic to the HSL family of esterases as identified by Arpigny and Jaeger (1999).''']]


- Similar structure and sequence.
- Characterised by their sequence similarity to the mammalian hormone sensitive lipase. Surprisingly, a mammalian HSL was not returned in the BLAST search.
 
- Association may be purely structural.


- '''Ecological evidence:''' Weak - an aquatic organism widely present throughout world's oceans.


[[Arylformamidase Function Slide 6| ...Previous slide ]]|[[Arylformamidase| Return to the main page ]]|[[Arylformamidase Function Slide 8| Next slide... ]]
[[Arylformamidase Function Slide 6| ...Previous slide ]]|[[Arylformamidase| Return to the main page ]]|[[Arylformamidase Function Slide 8| Next slide... ]]

Latest revision as of 14:07, 8 June 2008

Identification of family.

- Byun, et al. (2007) alluded to the HSL family of lipases.

- All known structures of the HSL family of esterases (Byun, et al. 2007) are present in the DALI search.

Structures of the HSL family of esterases as identified by Byun, et al. (2007) present in the DALI results.

- 2pbl shares sequence similarity in regions characteric to the HSL family of esterases (Arpigny and Jaeger 1999).

Sequence similarity in regions characteristic to the HSL family of esterases as identified by Arpigny and Jaeger (1999).

- Characterised by their sequence similarity to the mammalian hormone sensitive lipase. Surprisingly, a mammalian HSL was not returned in the BLAST search.

- Association may be purely structural.


...Previous slide | Return to the main page | Next slide...