Arylformamidase Function Slide 8

Thermostable?

- Byun, et al. (2007) identified a number of HSL family members with thermostable properties.

Thermophillic HSL family members as identified by Byun, et al. 2007 found in the DALI search performed by Basma.

- Similar sequence in regions characteristic to this family of proteins (Arpigny and Jaeger 1999).

- Similar structure and sequence.

- Ecological evidence: Weak - an aquatic organism widely present throughout world's oceans.

The Putative Function Refined

Exact function difficult to specify.

Broad range of functions performed by HSLs.

May be a thermostable carboxylesterase.

Applications?

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