Arylformamidase Structure: Difference between revisions

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Thioesterases split ester groups into acid and alcohol in the presence of water, specifically at a thiol group
Thioesterases split ester groups into acid and alcohol in the presence of water, specifically at a thiol group.


Thioesterases or thiolester hydrolases are members of E.C.3.1.2.
Thioesterases or thiolester hydrolases are members of E.C.3.1.2.
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This image was generated from ["STRINGS"]
This image was generated from "STRING" database.





Revision as of 02:22, 20 May 2008

1. Structure of Arylformamidase

Arylformamidase


Whole protein.png

The image above shows the chains A (upper right), B (upper left), C (lower right) & D (lower left) interacting. The molecules in the middle of chains A & B and chains C & D is phosphate ion (PO4). The green molecule between chain B & D is a magnesium ion (Mg).



Chain A of arylformamidase


Chain A.jpg

The red molecule in the middle is an unknown ligand containing a ring composed of 9 oxygen molecules. The green sphere is a chloride ion.



2. Putative Thioesterase

Thioesterases split ester groups into acid and alcohol in the presence of water, specifically at a thiol group.

Thioesterases or thiolester hydrolases are members of E.C.3.1.2.

Our structure resembles carboxylesterases (hydrolases) hence it is predicted that it has similar cellular activity.



3. Interaction of human arylformamidase with other proteins

Confidence interaction with names.png


This image was generated from "STRING" database.



4. DALI OUTPUT

File:DALI RESULT.txt



Carboxylesterase A chain

Carboxylase A chain.PNG

File:Carboxylase.txt

PDB link title


Archeaon Carboxylesterase (Chains A B C D)

Archeaon Carboxylesterase.PNG

File:Carboxylesterase (archaeon).txt

PDB link title



5. Secondary structure analysis

PDBSum output for arylformamidase

PDBSum pblA.PNG

PDBSUM [1]



6. Topology

Topology.gif

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