Coenzyme A Synthase's Relation To Other Structurally Related Proteins: Difference between revisions

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|'''Top fourteen structurally related proteins were all Kinases and some examples are:'''
|'''Top fourteen structurally related proteins were all Kinases and some examples are:'''
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* Thymidylate Kinase
* ''Thymidylate Kinase''
** Which catalyses reversible phosphorylation transfer from ATP & TMP to ADP & TDP.
** Which catalyses reversible phosphorylation transfer from ATP & TMP to ADP & TDP.
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* Shikimate Kinase
* ''Shikimate Kinase''
** Which is found in plants and catalyses reaction of phosphoryltransfer from ATP to shikimic acid.
** Which is found in plants and catalyses reaction of phosphoryltransfer from ATP to shikimic acid.
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* Adenylate Kinase
* ''Adenylate Kinase''
** Which catalyzes the production of ATP from ADP.
** Which catalyzes the production of ATP from ADP.
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* Dephospho-COA Kinase
* ''Dephospho-COA Kinase''
** Which is actually the DPCK domain of CoAsy, so it uses ATP as phosphate donor in phosphorylation of 3-hydroxy group of ribose in the COA synthesis pathway.
** Which is actually the DPCK domain of CoAsy, so it uses ATP as phosphate donor in phosphorylation of 3-hydroxy group of ribose in the COA synthesis pathway.
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Revision as of 18:14, 11 June 2007

The secondary structure of Mus musculus with indicated ligand interaction sites. Reproduced from, EMBL EBI, 2005
 Top fourteen structurally related proteins were all Kinases and some examples are:


  • Thymidylate Kinase
    • Which catalyses reversible phosphorylation transfer from ATP & TMP to ADP & TDP.


  • Shikimate Kinase
    • Which is found in plants and catalyses reaction of phosphoryltransfer from ATP to shikimic acid.


  • Adenylate Kinase
    • Which catalyzes the production of ATP from ADP.


  • Dephospho-COA Kinase
    • Which is actually the DPCK domain of CoAsy, so it uses ATP as phosphate donor in phosphorylation of 3-hydroxy group of ribose in the COA synthesis pathway.


Structural comparison of Dephospho-COA Kinase (IJJV) and Bifunctional coenzyme A synthase from Mus musculus (2F6R) with bound ATP.

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