DHRS1 Results: Difference between revisions

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[[Image:align 2uvd.png|framed|'''Figure 2'''<BR>Cartoon of DHRS1 (cyan/magenta) aligned with Oxoacyl-(Acyl-Carrier-protien)(green/red) the key catalytic Tyrosine residue is shown in as well. |none]]<BR>
[[Image:align 2uvd.png|framed|'''Figure 2'''<BR>Cartoon of DHRS1 (cyan/magenta) aligned with Oxoacyl-(Acyl-Carrier-protien)(green/red) the key catalytic Tyrosine residue is shown in as well. |none]]<BR>


[[Image:StrappedTree.png|1050px|'''Figure 3'''<BR>Phylogenetic Tree of SDR Family with Bootstrapping values|none]]<BR>
[[Image:StrappedTree.png|framed|'''Figure 3'''<BR>Phylogenetic Tree of SDR Family with Bootstrapping values|1050px]]<BR>


[[Image:Dehydrogenasereductase (SDR family) member 1 phylogram.png|framed|'''Figure 4'''<BR>Unrooted phylogram for Dehydrogenase/reductase (SDR family)|none]]<BR>
[[Image:Dehydrogenasereductase (SDR family) member 1 phylogram.png|framed|'''Figure 4'''<BR>Unrooted phylogram for Dehydrogenase/reductase (SDR family)|none]]<BR>

Revision as of 08:51, 20 May 2008

Figure 1
DHRS1 Gene expression pattern. Reproduced from Genomics Institute of Novartis Research Foundation. 2008


Figure 2
Cartoon of DHRS1 (cyan/magenta) aligned with Oxoacyl-(Acyl-Carrier-protien)(green/red) the key catalytic Tyrosine residue is shown in as well.


Figure 3
Phylogenetic Tree of SDR Family with Bootstrapping values


Figure 4
Unrooted phylogram for Dehydrogenase/reductase (SDR family)


Table 1

PDB/chain identifiers and structural alignment statistics for DALI search

No:	Chain	Z	rmsd	lali	nres	%id	Description
1:	2qq5-A	48.1	0.0	238	238	100	MOL:DEHYDROGENASE/REDUCTASE SDR1;
2:	2uvd-A	29.6	2.1	220	246	27	MOL: 3-OXOACYL-(ACYL-CARRIER-PROTEIN)  REDUCTASE;             
3:	1yde-F	29.3	2.1	216	256	29	MOL: RETINAL DEHYDROGENASE/REDUCTASE 3;                         
4:	1vl8-B	29.1	2.0	220	252	27	MOL: GLUCONATE 5-DEHYDROGENASE;                                 
5:	2bgk-A	29.0	2.1	219	267	25	MOL: RHIZOME SECOISOLARICIRESINOL DEHYDROGENASE; 
6:	2q2q-D	28.9	2.0	217	255	26	MOL: BETA-D-HYDROXYBUTYRATEDEHYDROGENASE;                                
7:	1rwb-F	28.8	2.2	221	261	24	MOL: GLUCOSE 1-DEHYDROGENASE;                                   
8:	1rwb-A	28.8	2.3	222	261	24	MOL: GLUCOSE 1-DEHYDROGENASE;                                   
9:	1gee-A	28.8	2.3	222	261	24	MOL: GLUCOSE 1-DEHYDROGENASE;                                   
10:	1gco-A	28.8	2.3	222	261	24	MOL: GLUCOSE DEHYDROGENASE;                                     
11:	2zat-A	28.7	2.1	221	251	23	MOL: DEHYDROGENASE/REDUCTASE SDR4;
12:	1gee-B	28.7	2.3	221	261	24	MOL: GLUCOSE 1-DEHYDROGENASE;                                   
13:	1gco-E	28.7	2.3	221	261	24	MOL: GLUCOSE DEHYDROGENASE;