Function: Difference between revisions

From MDWiki
Jump to navigationJump to search
No edit summary
No edit summary
 
(48 intermediate revisions by 3 users not shown)
Line 1: Line 1:
=='''Proposed Functions'''==
The predicted function based on the evolution and structure


* Hydrolase Activity
<font size = "4">'''Hydrolase'''</font>


* Magnesium Ion Binding


* N-acylneuraminate-9-phosphatase Activity
[[Image:Document18_01.png]]


* Phosphoglycolate Phosphatase Activity
Hydrolyase catalyze the hydrosis of the chemical bond between A and B, resulting of 2 simple molecules




[http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0016787 1. Hydrolase Activity]
* Hydrolase  
** Catalyze hydrolysis reaction 
** Addition of the hydrogen and hydroxyl ions of water
** Splitting into 2 or more simpler molecules
** EC class 3


[http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0000287 2. Magnesium Ion Binding]


[http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0050124 3. N-acylneuraminate-9-phosphatase Activity]


[http://amigo.geneontology.org/cgi-bin/amigo/go.cgi?view=details&depth=1&query=0008967 4. Phosphoglycolate Phosphatase Activity]
== Function of sulfatases ==


Sulfatases are enzymes,which hydrolyse sulfate ester bonds of substrates.
Most of the family members has shown to contain a highly conserved cystine residue and a bivalent metal binding site.




info


N-acetylneuraminic acid phosphatase


Homologous to mouse (Mus musculus)


Haloacid Dehalogenase Like Hydrolase Domain Containing 4
== Functional site==
MSA data revealed some conserved residues on the sequence. They were mapped on the three dimantional structure.


Classified as Hydrolase 
[[Image:Zn_Cl_surface]]


[http://www.ebi.ac.uk/thornton-srv/databases/profunc/index.html Infomation on ProFunc] (useful 2gfhA)
----


 
Click here to go [http://compbio.chemistry.uq.edu.au/mediawiki/index.php/BIOL3004_2007 ''Back'']
=='''GO Terms'''==
Polymer: haloacid dehalogenase-like hydrolase domain containing 4
 
Molecular Function: None
 
Biological Process: None
 
Cellular Component: None
 
 
[http://compbio.chemistry.uq.edu.au/mediawiki/index.php/BIOL3004_2007 Back]

Latest revision as of 09:44, 20 May 2008

The predicted function based on the evolution and structure

Hydrolase


Document18 01.png

Hydrolyase catalyze the hydrosis of the chemical bond between A and B, resulting of 2 simple molecules


  • Hydrolase
    • Catalyze hydrolysis reaction
    • Addition of the hydrogen and hydroxyl ions of water
    • Splitting into 2 or more simpler molecules
    • EC class 3


Function of sulfatases

Sulfatases are enzymes,which hydrolyse sulfate ester bonds of substrates. Most of the family members has shown to contain a highly conserved cystine residue and a bivalent metal binding site.



Functional site

MSA data revealed some conserved residues on the sequence. They were mapped on the three dimantional structure.

File:Zn Cl surface

Click here to go Back

Retrieved from "http://compbio.biosci.uq.edu.au/mediawiki/index.php?title=Function&oldid=7072"