Function for haloacid dehalogenase-like hydrolase domain containing 2: Difference between revisions
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[http://www.rcsb.org/pdb/ligand/ligandsummary.do?handler=biologyChemistry&hetId=PO4 / PO4] | [http://www.rcsb.org/pdb/ligand/ligandsummary.do?handler=biologyChemistry&hetId=PO4 / PO4] | ||
[[Image:PO4_400.gif]] [http://www.rcsb.org/pdb/ligand/ligandsummary.do?handler=biologyChemistry&hetId=MG / MG] | [[Image:PO4_400.gif]] | ||
[[Image:MG_400.gif]] [http://www.rcsb.org/pdb/ligand/ligandsummary.do?handler=biologyChemistry&hetId=MSE / MSE] | [http://www.rcsb.org/pdb/ligand/ligandsummary.do?handler=biologyChemistry&hetId=MG / MG] | ||
[[Image:MG_400.gif]] | |||
[http://www.rcsb.org/pdb/ligand/ligandsummary.do?handler=biologyChemistry&hetId=MSE / MSE] | |||
[[Image:MSE 400.gif]] | [[Image:MSE 400.gif]] | ||
Revision as of 02:33, 5 June 2007
Haloacid dehalogenase-like hydrolase domain containing 2 (2HO4:A,B)
Where's does this name come from? We look at it's name.
Hydolase indicates it's main molecular function, hydrolase activity.
And, Domain containing 2 illustrate it has 2 domains / Sequence and Secondary Structure
From the above diagram, we see 2 domain color in blue and purple showed separately.
Type: polypeptide(L)
Length: 259 residues
Secondary Structure: 44% helical (14 helices; 123 residues) 17% beta sheet (12 strands; 48 residues)
2HO4Aa: pdp domain 2HO4Aa (in purple)
2HO4Ab: pdp domain 2HO4Ab (in blue)
But this does not conclude all it's function
From the Protein Data Bank (PDB) /PBD Biology and Chemistry Report
We found it has 3 Ligands and Prosthetic Groups
ID Name Chemical Formula Weight Ligand PO4 Phosphate Ion O4 P 3- 94.971 MG Magnesium Ion Mg 2+ 24.305 MSE Selenomethionine C5 H11 N O2 Se 196.107
CDS 1..259
/gene="HDHD2"
/coded_by="NM_032124.4:134..913"
/GO_function="hydrolase activity"
/GO_process="metabolism"
/db_xref="CCDS:CCDS32829.1"
/db_xref="GeneID:84064"
/db_xref="HGNC:25364"
/db_xref="HPRD:13640"
GO_function:/ hydrolase activity
GO_process:/ metabolic process
Gene Detail:/ Hdhd2
FASTA of HDHD2 of haloacid dehalogenase-like hydrolase domain containing 2 Homo sapiens
COExpresson of Predict Functional Protein:/ HDHD2 haloacid dehalogenase-like hydrolase domain containing 2
ProFunc Result:/ 2ho4
HDHD2 (259 aa) (Homo sapiens) is highly conservatity to Pan troglodytes, Macaca mulatta, Rattus norvegicus, Mus musculus species.
Predicted Functional Partners: KIAA0423 annotation not available (1723 aa)
/ Gene Ontology Classifications
