Functional Analysis: Difference between revisions

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http://www.proteinscience.org/cgi/content/full/15/6/1527
http://www.proteinscience.org/cgi/content/full/15/6/1527


== Sequence -> Function ==
*Detecting Protein Function and Protein-Protein Interactions from Genome Sequences
Edward M. Marcotte, Matteo Pellegrini, Ho-Leung Ng, Danny W. Rice, Todd O. Yeates, and David Eisenberg (30 July 1999)
Science 285 (5428), 751. [DOI: 10.1126/science.285.5428.751]
http://www.sciencemag.org/cgi/content/short/285/5428/751


== Using mouse sequence: ==
== Using mouse sequence: ==

Revision as of 06:04, 22 May 2007

Gaf Domain

New avenues in protein function prediction http://www.proteinscience.org/cgi/content/full/15/6/1527


Sequence -> Function

  • Detecting Protein Function and Protein-Protein Interactions from Genome Sequences

Edward M. Marcotte, Matteo Pellegrini, Ho-Leung Ng, Danny W. Rice, Todd O. Yeates, and David Eisenberg (30 July 1999) Science 285 (5428), 751. [DOI: 10.1126/science.285.5428.751] http://www.sciencemag.org/cgi/content/short/285/5428/751

Using mouse sequence:

Locate Analysis

Mammalian Orthology http://www.informatics.jax.org/searches/homology_report.cgi?_Marker_key=92352 -- Genes

Mammalian Orthology http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=17580 --Proteins

String returned no results.

Pfam didn't work...http://www.sanger.ac.uk/cgi-bin/Pfam/getblast?id=2103981H86007039eB664

Profunc http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/profunc/GetResults.pl?source=profunc&user_id=ay41&code=073806

Interpro returned no results.

CDART http://www.ncbi.nlm.nih.gov/Structure/lexington/lexington.cgi?cmd=rps - when given a protein query sequence, CDART displays the functional domains that make up the protein and lists proteins with similar domain architectures. Returns no results for mouse sequence.