Locating The Bind Site For ACO In Coenzyme A Synthase: Difference between revisions

Revision as of 06:37, 11 June 2007


Surface map of Mus musculus Coenzyme A Synthase with electrostatic charge indicated, ATP ligand is included at P-Loop bind site of DPCK domain and ACO at the proposed Dephospho Coenzyme A Kinase cleft.	Location of binding clefts on Coenzyme A Synthase Mus. musculus with ACO and an unknown ligand (UNL).
Structures of Dephospho-CoA (A) and Acetyl-CoA (B). Structure of dephospho-CoA was reproduced from Daugherty et. al., 2002. Structure of Acetyl-CoA was reproduced from Baggot & Dennis, 1998.

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-|[[Image:COASYApbs_mapped_binding_cradle_shown_with_aligned_DPCK_IJJV_and_associated_ATP_ligand_biniding.jpg|thumb|500px|Surface map of ''Mus  musculus'' Coenzyme A Synthase with electrostatic charge indicated, ATP ligand is included at P-Loop bind site of DPCK domain and ACO at the proposed Dephospho Coenzyme A Kinase cleft.|none]]<BR>
+|[[Image:COASYApbs_mapped_binding_cradle_shown_with_aligned_DPCK_IJJV_and_associated_ATP_ligand_biniding.jpg|thumb|450px|Surface map of ''Mus  musculus'' Coenzyme A Synthase with electrostatic charge indicated, ATP ligand is included at P-Loop bind site of DPCK domain and ACO at the proposed Dephospho Coenzyme A Kinase cleft.|none]]<BR>
 |[[Image:COASYClefts.jpg|thumb|400px|Location of binding clefts on Coenzyme A Synthase Mus. musculus with ACO and an unknown ligand (UNL).|none]]
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