Pyridoxal Phosphatase Discussion

From MDWiki
Revision as of 03:06, 31 May 2008 by Sitoh Kheng Wai (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigationJump to search

Evolution



Structure


Based on the information obtained from PDB, 2cfsA was identified to have the following features:

  • Isolated from Homo Sapiens, and is expressed in Escherichia Coli.
  • Structurally similar to the Pyridoxal Phosphate Phosphatase protein.
  • Consists of a single type of chain (A), and (2) Magnesium components.
  • Resolution of 2.4 angstroms. The significance of this is that the probability that the number of side-chains in the wrong rotamer is relatively smaller. Proteins of similar resolution were noted also to: (1) have many small detectable errors, (2) be of correct folding, (3) contain fewer number of errors in the surface loops and (4) consist of visible water molecules and small ligands.

After running a search on the protein in the Dali database

Function