Result of SNAPG: Difference between revisions

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== SNAPG Structure ==
== SNAPG Structure ==
=== Sructure architecture ===
=== Structure architecture ===
SNAPG protein structure obtained from ''Dario rerio'' organism comprises of 4 molecular chains (Chain A,B,C and D).
SNAPG protein structure obtained from ''Dario rerio'' organism comprises of 4 molecular chains (Chain A,B,C and D).



Revision as of 14:32, 10 June 2007

SNAPG Structure

Structure architecture

SNAPG protein structure obtained from Dario rerio organism comprises of 4 molecular chains (Chain A,B,C and D).

In order to analyze protein structure of SNAPG, structural comparison to known protein structure is required. An insight to SNAPG structural arrangement provides various informative data on possible protein functions and interactions with another protein and/or DNA. Based on protein families database, Pfam at Sanger, it was found that SNAPG protein matched to Pfam-B protein families and consist of 2 domains, Pfam-B_7270 (PB007270) and Pfam-B_15198 (PB015189) respectively as shown in Figure 1. Both of 2 domains appears to be associated with NSF attachment protein activity [1].

Figure 1. Two domains of SNAPG protein (chain A)


2ifuA interpro.png


Structural comparison

Dali webserver is one of the powerful tool to screen any protein that are structurally homologous with our query. Two structurally related proteins with highest Z-value generated by Dali server were chosen for SNAPG structure comparison analysis. these proteins were protein binding .. (1qqe) and protein transport ... (2f17) (refer to table..)