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'''Structure of tRNA isopentenyltransferase'''
=='''Structure of tRNA isopentenyltransferase'''==





Revision as of 07:17, 27 May 2008

Structure of tRNA isopentenyltransferase

Localisation Expression of tRNA isopentenyltransferase

Generally, this enzyme is expressed in all tissue types since it is important that functional protein are synthesized in each of these tissues. Specifically, it is highly expressed in adipose tissues as well as oocytes. Relatively high amounts of this enzyme is expressed in prostate, adrenal gland, B-cells and trachea. The reason why tRNA-IPT are at higher concentrations in these tissues may reflect higher levels of protein synthesis.


Geneatlas mouse.png


Domain and Structural Analysis



Structural Elements and Functional Binding Sites of tRNA isopentenyltransferase


-Residue Flexibility -Hydrophobicity LOCATE results show that this enzyme is soluble in nature; although a small part of the protein terminus is hydrophobic.

-Functional Sites Found By Pattern Search

Table 1 

-Functional Sites Found by Sequence Conservation In Structurally Related Proteins -Functional Sites Found by Structure Conservation In Structurally Related Proteins -Multiple Sequence Alignment

Tree