Role in Human: Difference between revisions

Revision as of 23:26, 10 June 2007

Role in Human

Dephosphorylation of Neu5Ac-9-P is a reversible reaction with an end product of Neu5Ac (sialic acid) and a free phosphate.

Main form of sialic acid in vertebrates
- Important roles in protein-protein and cell-cell recognition
- Dependent on the presence of Mg²⁺
- Inhibited by vanadate and Ca²⁺

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-<font size = "4">'''Role in Bacteria - ''E.coli'''''</font>
+<font size = "4">'''Role in Human'''</font>
-* Hydrolyze a wide range of phosphorylated metabolites
+* OMIM
-** Carbohydrates
+** Haloacid dehalogenase-like hydrolase domain
-** Nucleotides,
+** Gene map locus 20p11
-** Organic acids
-* Kuznetsova ''et al'' - glycolysis and pentose phosphate pathway
+[[Image:Document2_01.png]]
-** Fructose-1-phosphate
-** Glucose-6-phosphate
-** Mannose-6-phosphate
-** 2-deoxyglucose-6-phosphate
-** Fructose-6- phosphate
-** Ribose-5-phosphate
-** Erythrose- 4-phosphate
+Dephosphorylation of Neu5Ac-9-P is a reversible reaction with an end product of Neu5Ac (sialic acid) and a free phosphate.
-[[Image:Document20_01.png]]
-[[Image:Document20_02.png]]
+* Main form of sialic acid in vertebrates
+** Important roles in protein-protein and cell-cell recognition
+** Dependent on the presence of Mg<sup>2+</sup>
+** Inhibited by vanadate and Ca<sup>2+</sup>
-Schematic diagrams of glycolysis and pentose phosphate metabolic pathways. The green arrows show the substrates that are hydrolyzed by HADs (http://www.steve.gb.com/science/core_metabolism.html)
+[[Role in ''E.coil''|Next Page]]
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