Strings 2008 1 1: Difference between revisions

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== 1 Background: Biological sequences ==
== 1 Background: Biological sequences ==
* DNA, RNA, protein
** universal molecules of life (from tiny micro-organisms to large mammals)
** state the chemical structure of DNA, RNA and protein
*** [http://en.wikipedia.org/wiki/DNA DNA]: 4 nucleotides, double helix, base pairing
*** [http://en.wikipedia.org/wiki/RNA RNA]: 4 nucleotides, single stranded
*** [http://en.wikipedia.org/wiki/Protein protein]: 20 amino acids, complex 3D structure
* [http://en.wikipedia.org/wiki/Central_dogma central dogma of molecular biology]
** = transfer of sequence information from DNA (mastercopy) to RNA (blueprint) to protein (construct)
** introduce terminology: transcription and translation
** universal code of life (from tiny micro-organisms to large mammals)
** introduce the concepts of reading frames and reverse compliment
* [http://en.wikipedia.org/wiki/Evolution evolution] and [http://en.wikipedia.org/wiki/Tree_of_life_%28science%29 tree of life]
** discuss how organisms are related (evolution) and how this relations can be represented (tree of life)
Reading material:


[[Media:chapter1_introduction.pdf | Chapter 1 from Zvelebil and Baum's Understanding bioinformatics]]<br>
[[Media:chapter1_introduction.pdf | Chapter 1 from Zvelebil and Baum's Understanding bioinformatics]]<br>
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[[strings_2008_2_1| goto Comparing sequences]]
[[strings_2008_2_1| goto Comparing sequences]]
--[[User:ThomasHuber|ThomasHuber]] 15:26, 17 January 2008 (EST)

Latest revision as of 04:26, 17 January 2008

1 Background: Biological sequences

  • DNA, RNA, protein
    • universal molecules of life (from tiny micro-organisms to large mammals)
    • state the chemical structure of DNA, RNA and protein
      • DNA: 4 nucleotides, double helix, base pairing
      • RNA: 4 nucleotides, single stranded
      • protein: 20 amino acids, complex 3D structure
  • central dogma of molecular biology
    • = transfer of sequence information from DNA (mastercopy) to RNA (blueprint) to protein (construct)
    • introduce terminology: transcription and translation
    • universal code of life (from tiny micro-organisms to large mammals)
    • introduce the concepts of reading frames and reverse compliment
  • evolution and tree of life
    • discuss how organisms are related (evolution) and how this relations can be represented (tree of life)


Reading material:

Chapter 1 from Zvelebil and Baum's Understanding bioinformatics



goto Comparing sequences


--ThomasHuber 15:26, 17 January 2008 (EST)