Strings 2008 2 5: Difference between revisions
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Biological sequences may not be perfectly identical because of | Biological sequences may not be perfectly identical because of | ||
# experimental errors that may have occurred in the determination of the sequence, | # experimental errors that may have occurred in the determination of the sequence, | ||
# mutations Sequences may have changed in course of evolution | # mutations. Sequences may have changed in course of evolution | ||
Further, biologist more often want to find other sequences that are similar to their sequence of interest then to re-identify identical sequences. | Further, biologist more often want to find other sequences that are similar to their sequence of interest rather then to re-identify identical sequences. | ||
In the next sections we will explore how to compare and search for similar sequences. | |||
== How can sequences change == | |||
== How can sequences change (class room brain storming) == | |||
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Compare these changes with the changes you would expect comparing DNA sequences. | Compare these changes with the changes you would expect comparing DNA sequences. | ||
|} | |} | ||
[[Strings_2008_2_6 | goto How can biological sequences change]] | |||
--[[User:ThomasHuber|ThomasHuber]] 14:29, 10 January 2008 (EST) | |||
Latest revision as of 04:39, 16 January 2008
Similarity of sequences
In bioinformatic reality finding exact matches between sequences is not enough. Biological sequences may not be perfectly identical because of
- experimental errors that may have occurred in the determination of the sequence,
- mutations. Sequences may have changed in course of evolution
Further, biologist more often want to find other sequences that are similar to their sequence of interest rather then to re-identify identical sequences.
In the next sections we will explore how to compare and search for similar sequences.
How can sequences change (class room brain storming)
| Discovery question:
Imagine you have to type The quick brown fox jumps over the lazy dog 500 times on a type writer. What sort of changes in the text between the 500 versions are you likely to observe? Compare these changes with the changes you would expect comparing DNA sequences. |
goto How can biological sequences change
--ThomasHuber 14:29, 10 January 2008 (EST)
