Strings 2008 2 5
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Similarity of sequences
In bioinformatic reality finding exact matches between sequences is not enough. Biological sequences may not be perfectly identical because of
- experimental errors that may have occurred in the determination of the sequence,
- mutations Sequences may have changed in course of evolution
Further, biologist more often want to find other sequences that are similar to their sequence of interest then to re-identify identical sequences.
How can sequences change
| Discovery question:
Imagine you have to type The quick brown fox jumps over the lazy dog 500 times on a type writer. What sort of changes in the text between the 500 versions are you likely to observe? Compare these changes with the changes you would expect comparing DNA sequences. |
