Structure

Materials & Methods

1) Protein structural search on PyMOL, NCBI Entrez, InterPro and PDB databases

• PDB code: 3b5q

2) Comparing protein search with DALI server to identify similiar structures

Results

PDB

Figure 1.0 Structure of 3b5q

Discussion

Sequence

>gi|160286517|pdb|3B5Q|A Chain A, Crystal Structure Of A Putative Sulfatase (Np_810509.1) From Bacteroides Thetaiotaomicron Vpi-5482 At 2.40 A Resolution GXGLALCGAAAQAQEKPNFLIIQCDHLTQRVVGAYGQTQGCTLPIDEVASRGVIFSNAYVGCPLSQPSRA ALWSGXXPHQTNVRSNSSEPVNTRLPENVPTLGSLFSESGYEAVHFGKTHDXGSLRGFKHKEPVAKPFTD PEFPVNNDSFLDVGTCEDAVAYLSNPPKEPFICIADFQNPHNICGFIGENAGVHTDRPISGPLPELPDNF DVEDWSNIPTPVQYICCSHRRXTQAAHWNEENYRHYIAAFQHYTKXVSKQVDSVLKALYSTPAGRNTIVV IXADHGDGXASHRXVTKHISFYDEXTNVPFIFAGPGIKQQKKPVDHLLTQPTLDLLPTLCDLAGIAVPAE KAGISLAPTLRGEKQKKSHPYVVSEWHSEYEYVTTPGRXVRGPRYKYTHYLEGNGEELYDXKKDPGERKN LAKDPKYSKILAEHRALLDDYITRSKDDYRSLKVDADPRCRNHTPGYPSHEGPGAREILKRK

Links

Arylsulfatase sequence

Human sulfatases: a structural perspective to catalysis

Amino acid residues forming the active site of arylsulfatase A. Role in catalytic activity and substrate binding

Protein structure in PDB

Crystal Structure