Talk:Protein Function

Information From 8th May 2007

MIF4G is the middle domain of eukaryotic initiation factor 4G (eIF4G). It also occurs in NMD2p (non-sense mediated mRNA decay protein - it is involved in the non-sense mediated decay of mRNAs containing premature stop codons) and in CBP80 (Cap binding protein).

The protein binds eIF4A, eIF3, RNA and DNA Therefore part of function is to bind to RNA

Possibly located in the cytoplasm - See link to LOCATE. Mouse protein of similar seuqence in this location.

MIF4G starts residue 28 Ends 240 (mouse)

It is soluble and non-secreted.

PA74324.2 Riken cDNA 2310075612 Rik Protein - AAH26740, AAH55812(mouse), AAH33759(human)

AAH55812 - Rik Protein Mouse. Present in the cerebellum, Striatum, Eye, Wholebrain, Liver, Hippocampus, Hematopoietic Stem Cells and Kidney Accession No: BC055812.1