Pyridoxal Phosphatase function: Difference between revisions
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===General Annotation=== | ===General Annotation=== | ||
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===Known Functions=== | ===Known Functions=== | ||
'''Amino Acid Metabolism''' | '''Amino Acid Metabolism''' | ||
- transamination | |||
- transsulfuration | |||
- selenoamino acid metabolism | |||
- conversion of typtophan to niacin. | |||
'''Gluconeogenesis''' | '''Gluconeogenesis''' | ||
- Catalyse transamination reactions for gluconeogenesis. | |||
- Coenzyme for glycogen phosphorylase, which catalyse glycogenolysis. | |||
'''Neurotransmitter Synthesis''' | '''Neurotransmitter Synthesis''' | ||
Pyridoxal phosphate-dependent enzymes catalyses the biosynthesis of serotonin, epinephrine, norepinephrine and gamma-aminobutyric acid(The four important neurotranmsitters). | - Coenzyme for Pyridoxal phosphate-dependent enzymes, which catalyses the biosynthesis of serotonin, epinephrine, norepinephrine and gamma-aminobutyric acid(The four important neurotranmsitters). | ||
'''Histamine Synthesis''' | '''Histamine Synthesis''' | ||
- Metabolism of histamine. | |||
'''Hemoglobin Synthesis and Function''' | '''Hemoglobin Synthesis and Function''' | ||
- Synthesis of heme | |||
- Binds to two sites on hemoglobin, enhancing the oxygen binding of hemoglobin. | |||
'''Gene Expression''' | '''Gene Expression''' | ||
- Increases or decreases the expression of certain genes. | |||
===Sequence homology=== | ===Sequence homology=== |
Revision as of 01:39, 10 June 2008
General Annotation
Known Functions
Amino Acid Metabolism
- transamination - transsulfuration - selenoamino acid metabolism - conversion of typtophan to niacin.
Gluconeogenesis
- Catalyse transamination reactions for gluconeogenesis. - Coenzyme for glycogen phosphorylase, which catalyse glycogenolysis.
Neurotransmitter Synthesis
- Coenzyme for Pyridoxal phosphate-dependent enzymes, which catalyses the biosynthesis of serotonin, epinephrine, norepinephrine and gamma-aminobutyric acid(The four important neurotranmsitters).
Histamine Synthesis
- Metabolism of histamine.
Hemoglobin Synthesis and Function
- Synthesis of heme - Binds to two sites on hemoglobin, enhancing the oxygen binding of hemoglobin.
Gene Expression
- Increases or decreases the expression of certain genes.
Sequence homology
Structural Similarities
Location of Gene on Genome
Functional Expression in Tissue
Protein-Protein Interactions
Functional Prediction:
Cofactor of HSPD1 and play a role in protein folding.
Coenzyme for asparagine synthetase by interacting with TS11.
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