Chromosome 1 open reading frame 41 Structure: Difference between revisions
From MDWiki
Jump to navigationJump to search
Hana Hamzah (talk | contribs) No edit summary |
No edit summary |
||
(2 intermediate revisions by 2 users not shown) | |||
Line 1: | Line 1: | ||
''' | '''1)Structural similarities''' | ||
[[Image:Picture 1.png|centre|framed|'''Figure 5:''' DALI result showing the first 35 proteins that have similar structures to c1orf41. Even though the proteins are similar in structure they have very little sequence identity to c1orf41. 1xpw is c1orf41 but the structure was solved by NMR.]] | |||
'''2)Domain Classification''' | |||
[[Image:1TVG pfam.png|centre|framed|'''Figure 6:''' Pfam result indicated that our protein has a F5/8 type C domain, also known as the discoidin domain which is apart of galactose binding domain super family.]] | |||
'''3)Protein Structure''' | |||
Secondary structure | |||
[[Image: | [[Image:PDB sum 2.PNG|centre|framed|'''Figure 1:''' Representation of c1orf41 secondary structure as presented in PDBsum.]] | ||
Tertiary structure | |||
[[Image:1tvg ani.gif|centre|framed|'''Figure 2:''' This protein is monomeric, consisting of a single domain. There are 8 beta strands (yellow) and 2 alpha helices (purple). The secondary structures are folded into jelly roll barrel where four pairs of anti-parallel beta strands are organised to form a barrel-like structure.]] | |||
[[Image: | [[Image:Charge surface ani.gif|centre|framed|'''Figure 3:''' Electrostatic charge distribution on the surface of c1orf41.]] | ||
''' | [[Image:1tvg surface.png|centre|framed|'''Figure 4:''' Surface representation of c1orf41. The Ca (II) ion is located within a pocket of the protein. Sm (III) interacts with Asp92 on the protein but its presence was probably due to the method used in solving the phase problem during structure solution using x-ray crystallogrophy.]] | ||
''' | '''4)Possible ligand binding sites''' | ||
Line 62: | Line 57: | ||
[[Chromosome 1 open reading frame 41| | [[Chromosome 1 open reading frame 41 Evolution|Next]] |
Latest revision as of 06:25, 16 June 2009
1)Structural similarities
2)Domain Classification
3)Protein Structure
Secondary structure
Tertiary structure
4)Possible ligand binding sites