Cellular context (location): Difference between revisions
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[[Image: Untitled8.PNG|centre|thumb|600px|]] | [[Image: Untitled8.PNG|centre|thumb|600px|]] | ||
Figure One: Expression profile for fascin-1. Reproduced from GNF SymAtlas (Genomics Institute of Novartis Research Foundation. o http://symatlas.gnf.org/SymAtlas/symquery?q=71743) | |||
We can observe from the graph that highest levels of fascin-1 are prsent in B-lymphoblasts which are immature cells which typically differentiate to form mature lymphocytes. B lymphocyte activation is accompanied by extensive membrane ruffling and pseudopod formation, which appears to be mediated by fascin (refer micromechanics). | |||
Revision as of 15:02, 11 June 2009
The expression profile of Fascin-1 is consistent with its function. the expression profile is shown below in Figure 1.
Figure One: Expression profile for fascin-1. Reproduced from GNF SymAtlas (Genomics Institute of Novartis Research Foundation. o http://symatlas.gnf.org/SymAtlas/symquery?q=71743)
We can observe from the graph that highest levels of fascin-1 are prsent in B-lymphoblasts which are immature cells which typically differentiate to form mature lymphocytes. B lymphocyte activation is accompanied by extensive membrane ruffling and pseudopod formation, which appears to be mediated by fascin (refer micromechanics).
