Cellular context (location): Difference between revisions
From MDWiki
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 4: | Line 4: | ||
Figure One: Expression profile for fascin-1. Reproduced from GNF SymAtlas (Genomics Institute of Novartis Research Foundation. o http://symatlas.gnf.org/SymAtlas/symquery?q=71743) | Figure One: Expression profile for fascin-1. Reproduced from GNF SymAtlas (Genomics Institute of Novartis Research Foundation. o http://symatlas.gnf.org/SymAtlas/symquery?q=71743) | ||
We can observe from the graph that highest levels of fascin-1 are prsent in B-lymphoblasts which are immature cells which typically differentiate to form mature lymphocytes. B lymphocyte activation is accompanied by extensive membrane ruffling and pseudopod formation, which appears to be mediated by fascin (refer micromechanics). | We can observe from the graph that highest levels of fascin-1 are prsent in B-lymphoblasts which are immature cells which typically differentiate to form mature lymphocytes. B lymphocyte activation is accompanied by extensive membrane ruffling and pseudopod formation, which appears to be mediated by fascin (refer micromechanics). | ||
Revision as of 00:21, 16 June 2009
The expression profile of Fascin-1 is consistent with its function. the expression profile is shown below in Figure 1.
Figure One: Expression profile for fascin-1. Reproduced from GNF SymAtlas (Genomics Institute of Novartis Research Foundation. o http://symatlas.gnf.org/SymAtlas/symquery?q=71743)
We can observe from the graph that highest levels of fascin-1 are prsent in B-lymphoblasts which are immature cells which typically differentiate to form mature lymphocytes. B lymphocyte activation is accompanied by extensive membrane ruffling and pseudopod formation, which appears to be mediated by fascin (refer micromechanics).
