Chromosome 1 open reading frame 41 Structure

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Sialidase2.png

Based on the DALI result, sialidases have similar structures to our protein. However, the sequence identity between our protein and sialidase proteins are small (~22). Sialidases are enzymes that cleave sialic acids from various glyco-conjugates (Newsted et al., 2005).

Galactose oxidase.png

Another enzyme that our protein is similar in structure to is galactose oxidase. This enzyme catalyzes the oxidation of D-galactose to D-galacto-hexodialdose and H2O2 (Ito et al., 1991).

Pdb sum.png

This protein's secondary structure consists of 2 alpha helices and 9 beta sheets.

Pymol ss1.PNG

Pymol structure displaying the folding of the secondary structure. Red is alpha helices, yellow is beta sheets and green is random coils connecting the the sheets and helices.