Divergence of function: Difference between revisions
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The different cellular location of the enzyme => different function | The different cellular location of the enzyme => different function | ||
[[Sequence analysis of 2qgn|Evolution]] | |||
Latest revision as of 05:58, 10 June 2008
From LOCATE, --> mouse enzyme is found in cytosol and mitochondria
However, the human enzyme is found in the nucleus. --> Has a nuclear signal localization that is also found in yeast IPTs. --> This is not found in Bacillus halodurans(2qgn) --> Signal peptide sequence is found in the additional residues in humans and yeast. --> This may be the reason why human IPT is found in nucleus.
The different cellular location of the enzyme => different function
