Hypothetical protein Abstract: Difference between revisions

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'''Abstract'''
'''Abstract'''


Ribose and fucose are important substrates in the uptake of material by cells, as they are involved in numerous cellular functions. The RbsD/FucU superfamily proteins have been shown to be involved in the transport of these two sugars, by causing anomeric change in the sugars. 2ob5A hypothectical protein LOC282969 isoform 1 has been found to be a member of this superfamily. Structural, evolutionary and functional analysis found that this protein is specifically involved with fucose transport as a FucU protein. This was supported by the finding of major conserved regions between the two types of transporters and specific binding residues.  
Ribose and fucose are important substrates in the uptake of material by cells, and are involved in numerous cellular functions. RbsD/FucU proteins have been shown to be involved in the transport of these sugars, and may cause anomeric change in the sugars. 2ob5A hypothectical protein LOC282969 isoform 1 is a member of this superfamily. More specifically, through structural, evolutionary and functional bioinformatic analyses it has been found found that this protein participates in fucose transport (FucU family). It is suggested that the protein forms a decameric ring-shaped oligomer, in which major conserved regions and specific binding residues have been identified by comparison with RbsD transporter molecules.  
 


[[Hypothetical protein Abstract | Abstract ]] | [[Hypothetical protein Introduction | Introduction]] | [[Hypothetical protein Method| Method]] |  
[[Hypothetical protein Abstract | Abstract ]] | [[Hypothetical protein Introduction | Introduction]] | [[Hypothetical protein Method| Method]] |  

Latest revision as of 01:12, 16 June 2009

Abstract

Ribose and fucose are important substrates in the uptake of material by cells, and are involved in numerous cellular functions. RbsD/FucU proteins have been shown to be involved in the transport of these sugars, and may cause anomeric change in the sugars. 2ob5A hypothectical protein LOC282969 isoform 1 is a member of this superfamily. More specifically, through structural, evolutionary and functional bioinformatic analyses it has been found found that this protein participates in fucose transport (FucU family). It is suggested that the protein forms a decameric ring-shaped oligomer, in which major conserved regions and specific binding residues have been identified by comparison with RbsD transporter molecules.

Abstract | Introduction | Method | Results | Discussion | Conclusion | References


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