Structure Protein

2ifu has 4 chains (A, B, C and D) integrated together to form the whole molecular structure as shown below:

(chain A= green, chain B= cyan, chain c= purple, and chain d= yellow)

Two molecular components were observed:

sulfate ion (SO4) and selenomethionine (MSE)

Ten sulfate ions were observed. Each ion differs in arrangement as well as orientation related with each chains.

protein sequence (FASTA)

>gi|118138356|pdb|2IFU|A Chain A, Crystal Structure Of A Gamma-Snap From Danio Rerio AIAAQKISEAHEHIAKAEKYLKTSFXKWKPDYDSAASEYAKAAVAFKNAKQLEQAKDAYLQEAEAHANNR SLFHAAKAFEQAGXXLKDLQRXPEAVQYIEKASVXYVENGTPDTAAXALDRAGKLXEPLDLSKAVHLYQQ AAAVFENEERLRQAAELIGKASRLLVRQQKFDEAAASLQKEKSXYKEXENYPTCYKKCIAQVLVQLHRAD YVAAQKCVRESYSIPGFSGSEDCAALEDLLQAYDEQDEEQLLRVCRSPLVTYXDNDYAKLAISLKVPGGG GGKKKPSASASAQPQEEEDDEYAGGLC

Strutural comparisons

SNAP-GAMMA DALI

Based on Dali search, 6 proteins with highest Z-value were chosen: 1qqe-A (protein transport), 2fi7-A (protein binding), 1a17 (hydrolase), 2ak6-A, 1fch-A (signalling protein), 1haz4-A (transcription factor),

snap-gamma: multiple structure alignment

Snap-gamma: sequence alignment with 1QQE:A

Dark colors: 2ifu:A Light colors: 1qqe:A

SCOP

multiple alignment results, click here

Superimposed structure between 2ifuA; 2ifuB; 2ifuC; 2ifuD; 1qqeA; and 1b89A

Protein families

has 2 domains: Pfam at Sanger

alignment with:

Pfam-B_7270 (7-66)

highly conserved residue:

Pfam-B_15198 (87-307) highly conserved residue :residue 104, 109, 121, 168

scorecons result indicated a Diversity of position scores: 89.4% where 100%=high diversity

InterProScan Results

links

CRYSTAL STRUCTURE OF THE VESICULAR TRANSPORT PROTEIN SEC17 1QQE

CLATHRIN HEAVY CHAIN PROXIMAL LEG SEGMENT (BOVINE) 1B89

uniprot

http://myhits.isb-sib.ch/cgi-bin/motif_scan

http://www.ncbi.nlm.nih.gov/Structure/vast/vastsrv.cgi?sdid=181604

http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi