What's Coenzyme A?

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  • CoA is an essential cofactor.
    • Carries acyl and acetyl groups


  • Involved in many cellular processes - especially metabolic processes. These include, for example:
    • The tricarboxylic acid cycle
    • Beta-oxidation
    • Fatty acid synthesis


  • Associated with several disease and compromised metabolic states, including:
    • Starvation
    • Alcoholism
    • Diabetes
    • Some tumours


Structure of CoA

CoA structure 2.png

CoA structure.png

Reproduced from Wikipedia (Wikipedia: The Free Encyclopaedia (2007, 6 6) Coenzyme A - Wikepedia, The Free Encyclopaedia. Retrieved 9 6, 2007 from Wikipedia: http://en.wikipedia.org/wiki/Coenzyme_A)


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